This paper questions the effectiveness of a modern predictive uncertainty quantification approach, called evidential deep learning (EDL), in which a single neural network model is trained to learn a meta distribution over the predictive distribution by minimizing a specific objective function. Despite their perceived strong empirical performance on downstream tasks, a line of recent studies by Bengs et al. identify limitations of the existing methods to conclude their learned epistemic uncertainties are unreliable, e.g., in that they are non-vanishing even with infinite data. Building on and sharpening such analysis, we 1) provide a sharper understanding of the asymptotic behavior of a wide class of EDL methods by unifying various objective functions; 2) reveal that the EDL methods can be better interpreted as an out-of-distribution detection algorithm based on energy-based-models; and 3) conduct extensive ablation studies to better assess their empirical effectiveness with real-world datasets. Through all these analyses, we conclude that even when EDL methods are empirically effective on downstream tasks, this occurs despite their poor uncertainty quantification capabilities. Our investigation suggests that incorporating model uncertainty can help EDL methods faithfully quantify uncertainties and further improve performance on representative downstream tasks, albeit at the cost of additional computational complexity.

Federated learning (FL) allows collaborative machine learning training without sharing private data. While most FL methods assume identical data domains across clients, real-world scenarios often involve heterogeneous data domains. Federated Prototype Learning (FedPL) addresses this issue, using mean feature vectors as prototypes to enhance model generalization. However, existing FedPL methods create the same number of prototypes for each client, leading to cross-domain performance gaps and disparities for clients with varied data distributions. To mitigate cross-domain feature representation variance, we introduce FedPLVM, which establishes variance-aware dual-level prototypes clustering and employs a novel α- sparsity prototype loss. The dual-level prototypes clustering strategy creates local clustered prototypes based on private data features, then performs global prototypes clustering to reduce communication complexity and preserve local data privacy.

Patient mobility monitoring in intensive care is critical for ensuring timely interventions and improving clinical outcomes. While accelerometry-based sensor data are widely adopted in training artificial intelligence models to estimate patient mobility, existing approaches face two key limitations highlighted in clinical practice: (1) modeling the long-term accelerometer data is challenging due to the high dimensionality, variability, and noise, and (2) the absence of efficient and robust methods for long-term mobility assessment. To overcome these challenges, we introduce MELON, a novel multimodal framework designed to predict 12-hour mobility status in the critical care setting. MELON leverages the power of a dual-branch network architecture, combining the strengths of spectrogram-based visual representations and sequential accelerometer statistical features. MELON effectively captures global and fine-grained mobility patterns by integrating a pre-trained image encoder for rich frequency-domain feature extraction and a Mixture-of-Experts encoder for sequence modeling. We trained and evaluated the MELON model on the multimodal dataset of 126 patients recruited from nine Intensive Care Units at the University of Florida Health Shands Hospital main campus in Gainesville, Florida. Experiments showed that MELON outperforms conventional approaches for 12-hour mobility status estimation with an overall area under the receiver operating characteristic curve (AUROC) of 0.82 (95\%, confidence interval 0.78-0.86). Notably, our experiments also revealed that accelerometer data collected from the wrist provides robust predictive performance compared with data from the ankle, suggesting a single-sensor solution that can reduce patient burden and lower deployment costs...

Background: Circadian desynchrony characterized by the misalignment between an individual's internal biological rhythms and external environmental cues, significantly affects various physiological processes and health outcomes. Quantifying circadian desynchrony often requires prolonged and frequent monitoring, and currently, an easy tool for this purpose is missing. Additionally, its association with the incidence of delirium has not been clearly explored. Methods: A prospective observational study was carried out in intensive care units (ICU) of a tertiary hospital. Circadian transcriptomics of blood monocytes from 86 individuals were collected on two consecutive days, although a second sample could not be obtained from all participants. Using two public datasets comprised of healthy volunteers, we replicated a model for determining internal circadian time. We developed an approach to quantify circadian desynchrony by comparing internal circadian time and external blood collection time. We applied the model and quantified circadian desynchrony index among ICU patients, and investigated its association with the incidence of delirium. Results: The replicated model for determining internal circadian time achieved comparable high accuracy. The quantified circadian desynchrony index was significantly higher among critically ill ICU patients compared to healthy subjects, with values of 10.03 hours vs 2.50-2.95 hours (p < 0.001). Most ICU patients had a circadian desynchrony index greater than 9 hours. Additionally, the index was lower in patients whose blood samples were drawn after 3pm, with values of 5.00 hours compared to 10.01-10.90 hours in other groups (p < 0.001)...

Secure aggregation is motivated by federated learning (FL) where a cloud server aims to compute an averaged model (i.e., weights of deep neural networks) of the locally-trained models of numerous clients, while adhering to data security requirements. Hierarchical secure aggregation (HSA) extends this concept to a three-layer network, where clustered users communicate with the server through an intermediate layer of relays. In HSA, beyond conventional server security, relay security is also enforced to ensure that the relays remain oblivious to the users' inputs (an abstraction of the local models in FL). Existing study on HSA assumes that each user is associated with only one relay, limiting opportunities for coding across inter-cluster users to achieve efficient communication and key generation. In this paper, we consider HSA with a cyclic association pattern where each user is connected to $B$ consecutive relays in a wrap-around manner. We propose an efficient aggregation scheme which includes a message design for the inputs inspired by gradient coding-a well-known technique for efficient communication in distributed computing-along with a highly nontrivial security key design. We also derive novel converse bounds on the minimum achievable communication and key rates using information-theoretic arguments.

Acute brain dysfunction (ABD) is a common, severe ICU complication, presenting as delirium or coma and leading to prolonged stays, increased mortality, and cognitive decline. Traditional screening tools like the Glasgow Coma Scale (GCS), Confusion Assessment Method (CAM), and Richmond Agitation-Sedation Scale (RASS) rely on intermittent assessments, causing delays and inconsistencies. In this study, we propose MANDARIN (Mixture-of-Experts Framework for Dynamic Delirium and Coma Prediction in ICU Patients), a 1.5M-parameter mixture-of-experts neural network to predict ABD in real-time among ICU patients. The model integrates temporal and static data from the ICU to predict the brain status in the next 12 to 72 hours, using a multi-branch approach to account for current brain status. The MANDARIN model was trained on data from 92,734 patients (132,997 ICU admissions) from 2 hospitals between 2008-2019 and validated externally on data from 11,719 patients (14,519 ICU admissions) from 15 hospitals and prospectively on data from 304 patients (503 ICU admissions) from one hospital in 2021-2024. Three datasets were used: the University of Florida Health (UFH) dataset, the electronic ICU Collaborative Research Database (eICU), and the Medical Information Mart for Intensive Care (MIMIC)-IV dataset. MANDARIN significantly outperforms the baseline neurological assessment scores (GCS, CAM, and RASS) for delirium prediction in both external (AUROC 75.5% CI: 74.2%-76.8% vs 68.3% CI: 66.9%-69.5%) and prospective (AUROC 82.0% CI: 74.8%-89.2% vs 72.7% CI: 65.5%-81.0%) cohorts, as well as for coma prediction (external AUROC 87.3% CI: 85.9%-89.0% vs 72.8% CI: 70.6%-74.9%, and prospective AUROC 93.4% CI: 88.5%-97.9% vs 67.7% CI: 57.7%-76.8%) with a 12-hour lead time. This tool has the potential to assist clinicians in decision-making by continuously monitoring the brain status of patients in the ICU.

Query-focused tabular summarization is an emerging task in table-to-text generation that synthesizes a summary response from tabular data based on user queries. Traditional transformer-based approaches face challenges due to token limitations and the complexity of reasoning over large tables. To address these challenges, we introduce DETQUS (Decomposition-Enhanced Transformers for QUery-focused Summarization), a system designed to improve summarization accuracy by leveraging tabular decomposition alongside a fine-tuned encoder-decoder model. DETQUS employs a large language model to selectively reduce table size, retaining only query-relevant columns while preserving essential information. This strategy enables more efficient processing of large tables and enhances summary quality. Our approach, equipped with table-based QA model Omnitab, achieves a ROUGE-L score of 0.4437, outperforming the previous state-of-the-art REFACTOR model (ROUGE-L: 0.422). These results highlight DETQUS as a scalable and effective solution for query-focused tabular summarization, offering a structured alternative to more complex architectures.

Current approaches to emotion detection often overlook the inherent subjectivity of affective experiences, instead relying on aggregated labels that mask individual variations in emotional responses. We introduce iNews, a novel large-scale dataset explicitly capturing subjective affective responses to news headlines. Our dataset comprises annotations from 291 demographically diverse UK participants across 2,899 multimodal Facebook news posts from major UK outlets, with an average of 5.18 annotators per sample. For each post, annotators provide multifaceted labels including valence, arousal, dominance, discrete emotions, content relevance judgments, sharing likelihood, and modality importance ratings (text, image, or both). Furthermore, we collect comprehensive annotator persona information covering demographics, personality, media trust, and consumption patterns, which explain 15.2% of annotation variance - higher than existing NLP datasets. Incorporating this information yields a 7% accuracy gain in zero-shot prediction and remains beneficial even with 32-shot. iNews will enhance research in LLM personalization, subjectivity, affective computing, and individual-level behavior simulation.

Federated learning (FL) is a useful tool that enables the training of machine learning models over distributed data without having to collect data centrally. When deploying FL in constrained wireless environments, however, intermittent connectivity of devices, heterogeneous connection quality, and non-i.i.d. data can severely slow convergence. In this paper, we consider FL with arbitrary device participation probabilities for each round and show that by weighing each device's update by the reciprocal of their per-round participation probability, we can guarantee convergence to a stationary point. Our bound applies to non-convex loss functions and non-i.i.d. datasets and recovers state-of-the-art convergence rates for both full and uniform partial participation, including linear speedup, with only a single-sided learning rate. Then, using the derived convergence bound, we develop a new online client selection and power allocation algorithm that utilizes the Lyapunov drift-plus-penalty framework to opportunistically minimize a function of the convergence bound and the average communication time under a transmit power constraint. We use optimization over manifold techniques to obtain a solution to the minimization problem. Thanks to the Lyapunov framework, one key feature of the algorithm is that knowledge of the channel distribution is not required and only the instantaneous channel state information needs to be known. Using the CIFAR-10 dataset with varying levels of data heterogeneity, we show through simulations that the communication time can be significantly decreased using our algorithm compared to uniformly random participation, especially for heterogeneous channel conditions.

Despite speaking mutually intelligible varieties of the same language, speakers of Tajik Persian, written in a modified Cyrillic alphabet, cannot read Iranian and Afghan texts written in the Perso-Arabic script. As the vast majority of Persian text on the Internet is written in Perso-Arabic, monolingual Tajik speakers are unable to interface with the Internet in any meaningful way. This paper presents a transformer-based G2P approach to Tajik-Farsi transliteration, achieving chrF++ scores of 58.70 (Farsi to Tajik) and 74.20 (Tajik to Farsi) on novel digraphic datasets, setting a comparable baseline metric for future work. Our results also demonstrate the non-trivial difficulty of this task in both directions. We also provide an overview of the differences between the two scripts and the challenges they present, so as to aid future efforts in Tajik-Farsi transliteration. Keywords: Persian, Tajik, Transliteration, Orthography, Computational Linguistics 1 Introduction Tajik Persian (henceforth, Tajik) is the formal variety of Modern Persian spoken in Tajikistan. As such, it retains an extremely high level of mutual intelligibility with formal Persian as spoken in Iran and Afghanistan (henceforth referred to as Farsi). Unlike these two countries which use the centuries-old Perso-Arabic script, Tajikistan uses the relatively new Tajik-Cyrillic script due to Tajikistan's Soviet heritage (Perry 2005). While proposals have been made to shift the script back to Perso-Arabic, any significant shift will likely not occur in the near future, with Tajikistan's former Minister of Culture stating in 2008 that "...some 90-95% of Tajikistan's population is not familiar with Arabic script..." 1 (Ghufronov 2008).